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With certain disorders of the heart or blood vessels. Plavix, or Clopidogrel bisulfate, is a prescription medication used to treat strokes. The medicine must be continued to use even until suggested by the doctor. Do not take aspirin, ibuprofen or naproxen without your doctor's advice. Patients to switch to the generic. Plavix tablets come in the antiplatelet drug category and helps prevent harmful blood clots. The anti-stroke drug Plavix instead of aspirin.